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What research
is being done?
The National Institute of Neurological Disorders and Stroke (NINDS) is
one of the federal government’s leading supporters of biomedical
research on brain and nervous system disorders. The NINDS conducts
research in its laboratories at the National Institutes of Health in
Bethesda, Maryland , and also awards grants to support research at
universities and other facilities.
Many of the Institutes at the NIH, including the NINDS, are sponsoring
research to understand what causes AS and how it can be effectively
treated. One study is using functional magnetic resonance imaging (fMRI)
to show how abnormalities in particular areas of the brain cause changes
in brain function that result in the symptoms of AS and other ASDs. A
large-scale study is comparing neuropsychological and psychiatric
assessments of children with possible diagnoses of AS or HFA to those of
their parents and siblings to see if there are patterns of symptoms that
link AS and HFA to specific neuropsychological profiles. A clinical
trial is testing the effectiveness of an anti-depressant in individuals
with AS and HFA who exhibit high levels of obsessive/ritualistic
behavior. Other investigators are conducting a long-range study to
collect and analyze DNA samples from a large group of children with AS
and HFA and their families to identify genes and genetic interactions
that are linked to AS and HFA.
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